B6.129S2-Igh-6tm1Cgn/J
Jackson Stock Number: 002288
Keywords
Animal Model B6.129S2-Igh-6tm1Cgn/J
Abstract
Mice homozygous for the Igh-6tm1Cgn targeted mutation are viable and fertile. Homozygous mutant mice lack mature B-cells. There is no expression of membrane-bound IgM, although some B-cells may be produced using a C gene other than mu. It may be useful as a model for B-cell immunodeficiency found in humans. Also know as muMT.
Immunology and Inflammation Research:
Immunodeficiency (B cell deficiency)
Research Tools:
Cancer Research (B cell deficiency)
Immunology and Inflammation Research (B cell deficiency)
Further Reading & Data Sheet
See information from The Jackson Laboratory
This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.