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B6.129S2-Igll1tm1Cgn/J

Jackson Stock Number: 002401

Keywords

Animal Model B6.129S2-Igll1tm1Cgn/J

Abstract

Mice homozygous for the Igl-5tm1Cgn mutation are viable and fertile. Homozygotes show a block in B cell development in bone marrow at the pre-B cell stage; however, blockage is leaky and a low percentage of B cells do get to the peripheral immune system.

Immunology and Inflammation Research:
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Immunodeficiency

Further Reading & Data Sheet

See information from The Jackson Laboratory


This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.