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Automatic 3D modelling of craniofacial bone defects

Reference Number TO 15-00343


Preoperative planning for computer-assisted surgery (CAS) for complex midfacial trauma requires accurate 3D models for reconstruction of bone defects. For one-sided defects of anatomical structures with mirror symmetry such as the scull, patient-specific computer models can easily be generated by mirroring the unaffected healthy half of the structure to the pathological side along the center line. However, neither complex fractures crossing the center line nor body parts with asymmetric geometry such as the knee joint can be modelled with this technique. Alternative methods for obtaining a complete image require manual or semi-automatic modelling procedures using reference data sets. As these methods are time-consuming and error-prone, and the quality of the images obtained depends largely on the experience of the surgeon, researchers are striving to improve the accuracy and ease of use of software tools for automated image reconstruction.

Automatic 3D modelling of craniofacial bone defects

Automatic 3D modeling of complex bone defects based on mirror symmetry.


The technology discloses a fast and accurate method for automatic 3D modeling of complex bone fractures or defects utilizing a data base of standard data sets that are automatically adapted to patient-specific data by means of a computer algorithm. A case study showed extremely low differences between the actual bony structure of the patient and a model generated according to the invention. The maximum deviation between model data and patient data was 2.5 mm or less.

Commercial Opportunity

In-licensing or collaboration for further development is possible.

Development Status

A proof-of-concept study has been conducted using scull data sets of different patients.

Patent Situation

US patent (US 9,639,977) was granted in 2017. European patent is expected to be granted soon.