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Antibodies

All antibodies are monoclonals unless stated otherwise. Depending on availability, antibodies can be delivered in TCS1, CSFS2, or purified:

4 ml TCS 250 €  |  4 ml CSFS 600 €  |  0,5 mg 600 €

To receive further information on an antibody of interest please contact Anja Zimmermann.

tissue culture supernatant 
concentrated serum free supernatant

 


TCR

Keywords

TCR; T-cell therapy; immunotherapy; oncology; cancer

10 hybridoma cell lines are offered that produce TCR-specific antibodies. These antibodies were raised by immunization with mouse/human TCR heterodimers. Antibodies of group A bind specificically to human AV chains and TCR heterodimers of human AV and mouse BV. Antibodies of group B bind specifically to human BV chains and TCR heterodimers of mouse AV and human BV. Nonetheless, none of the antibodies recognize fully human TCR as expressed on CD3+ peripheral blood lymphocytes. Apparently, these antibodies recognize conformational neo-epitopes of human TCR chains.