Mice homozygous for the Igh-Jtm1Cgn targeted mutation fail to produce functional B-cells as they lack the gene for the heavy chain joining region. Also known as JHT.
Immunology and Inflammation Research:
Immunodeficiency (B cell deficiency)
Immunology and Inflammation Research (B cell deficiency)
Further Reading & Data Sheet
This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.