Mice that are homozygous for the targeted mutation are viable, fertile and normal in size. Homozygous mice lack B220+ peripheral blood lymphocytes. This mutant mouse strain represents a model that may be useful in studies related to B-cell immunodeficiency
Immunology and Inflammation Research:Immunodeficiency (B cell deficiency)
Cancer Research (B cell deficiency)
Immunology and Inflammation Research (B cell deficiency)
Further Reading & Data Sheet
This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.