Mice homozygous for the Igk-Ctm1Cgn targeted mutation are viable and fertile. The number of B cells expressing l chain is increased 2-fold in heterozygotes and 7-fold in homozygotes.
Immunology and Inflammation Research:
CD Antigens, Antigen Receptors, and Histocompatibility Markers, Immunodeficiency
Further Reading & Data Sheet
This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.