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C57BL/6-Itgb7tm1Cgn/J

Jackson Stock Number: 002965

Abstract

Mice homozygous for the Itgb7tm1Cgn targeted mutation have a marked hypoplasia of the gut-associated lymphoid tissue (GALT). This deficit is apparently due to the failure of Itgb7-deficient lymphocytes to arrest and adhere in the GALT.

Cell Biology Research:
Defects in Cell Adhesion Molecules

Immunology and Inflammation Research:
Growth Factors/Receptors/Cytokines
Lymphoid Tissue Defects

Further Reading & Data Sheet

See information from The Jackson Laboratory


This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.