NOD.129S2-Igh-6tm1Cgn/Dvs (Stock #003903) at N10 was bred with NOD.B6-Tg(IghelMD4)4Ccg/Dvs (Stock #004253) then doubly heterozygous offspring were backcrossed to NOD.129S2-Igh-6tm1Cgn/Dvs (Stock #003903) to make the strain homozygous for Igh-6tm1Cgn then these mice were sibling mated to make this strain also homozygous for Tg(IghelMD4)4Ccg.
Immunology and Inflammation Research:
Immunodeficiency (B cell deficiency)
Cancer Research (B cell deficiency),
Immunology and Inflammation Research (B cell deficiency)
Further Reading & Data Sheet
See information from The Jackson Laboratory
This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.