This strain was derived from a cross between mice of strains NOD.B6-Itgb7tm1Cgn/Lt (Stock No. 004310), then at backcross generation N9, and NOD.129P2(B6)-Selltm1Tft/1Lt (Stock No. 3860), at backcross generation N10. Dr. Leiter transferred this stock to the T1DR in 2005.
Immunology and Inflammation Research:
CD Antigens, Antigen Receptors, and Histocompatibility Markers, Itgb7tm1Cgn related, Growth Factors/Receptors/Cytokines, Lymphoid Tissue Defects
Cell Biology Research:
Defects in Cell Adhesion Molecules
Further Reading & Data Sheet
This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.