B6.129S2-Igll1tm1Cgn/J
Jackson Stock Number: 002401
Keywords
Animal Model B6.129S2-Igll1tm1Cgn/J
Abstract
Mice homozygous for the Igl-5tm1Cgn mutation are viable and fertile. Homozygotes show a block in B cell development in bone marrow at the pre-B cell stage; however, blockage is leaky and a low percentage of B cells do get to the peripheral immune system.
Immunology and Inflammation Research:
CD Antigens, Antigen Receptors, and Histocompatibility Markers
Immunodeficiency
Further Reading & Data Sheet
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This animal model is bred and managed by The Jackson Laboratory and marketed for commercial use by Ascenion.