Antibodies
All antibodies are monoclonals unless stated otherwise. Depending on availability, antibodies can be delivered in TCS1, CSFS2, or purified:
4 ml TCS 250 € | 4 ml CSFS 600 € | 0,5 mg 600 €
To receive further information on an antibody of interest please contact Anja Zimmermann.
1 tissue culture supernatant
2 concentrated serum free supernatant
TCR
Keywords
TCR; T-cell therapy; immunotherapy; oncology; cancer
10 hybridoma cell lines are offered that produce TCR-specific antibodies. These antibodies were raised by immunization with mouse/human TCR heterodimers. Antibodies of group A bind specificically to human AV chains and TCR heterodimers of human AV and mouse BV. Antibodies of group B bind specifically to human BV chains and TCR heterodimers of mouse AV and human BV. Nonetheless, none of the antibodies recognize fully human TCR as expressed on CD3+ peripheral blood lymphocytes. Apparently, these antibodies recognize conformational neo-epitopes of human TCR chains.