Non-invasive and high-throughput monitoring of exon-specific isoform expression

Expansion of pancreatic progenitors derived from human pluripotent stem cells und GMP-compliant conditions

Biodynamers enhance drug delivery

Stable Gene Transfer with Hyperactive Sleeping Beauty Transposase SB100X

Improved Sleeping Beauty Transposon System for gene therapy: SB100X/pT4

CrispRGold - Design of efficient CrispR/Cas sgRNA sequences and off-target prediction

Homology Independent Genomic Sequence Replacement

Spacer-nick genome editing of hematopoietic stem and progenitor cells and T cells

Sleeping Beauty transposase variants with increased safety due to reduced half-life

Safer Sleeping Beauty transposase variants with improved integration profiles 

Activity-enhanced variant of hyperactive Sleeping Beauty transposase SB100X

AAV Vector Variants for Ocular Gene Delivery

Non-integrating alpharetrovirus-based vector particles for efficient RNA delivery and targeted gene modification

Maintenance of regulatory T cell phenotype by expression of IL-2 fusion protein

Reprogramming immune cells for CAR cell-based therapies

Immunosuppressant resistance in anti-viral T cell products 

High-level recombinant adeno-associated virus production

CD3-CAR NK-92 cell-mediated TCR+ depletion

Method for Assessing Out-of-Specification (OOS) CAR T-Cell Products and Predicting Patient Response

The CXCR3alt-CXCL11 chemokine system for therapeutic use in solid cancer

Base editing enzymes for multiplex editing with simultaneous gene knock-in and knock-out

An engineered serine integrase for targeted gene transfer in human cells

BreakTag - Novel method for detection of ds-breaks and analysis of CRISPR-induced on- and off-target effects

CRISPR Switch: Inducible sgRNA expression for tightly regulated, efficient and safer CRISPR/Cas9 genome editing

CRISPR StAR: facilitating high resolution genetic screening in complex in vivo models