Non-invasive and high-throughput monitoring of exon-specific isoform expression

AAV-based split-dCas9 gene activator system for in vivo reprogramming approaches

CRISPR/Cas13-based approach for the treatment of viral diseases caused by RNA viruses

Expansion of pancreatic progenitors derived from human pluripotent stem cells und GMP-compliant conditions

Biodynamers enhance drug delivery

Stable Gene Transfer with Hyperactive Sleeping Beauty Transposase SB100X

Improved Sleeping Beauty Transposon System for gene therapy: SB100X/pT4

Homology Independent Genomic Sequence Replacement

Spacer-nick genome editing of hematopoietic stem and progenitor cells and T cells

Safer Sleeping Beauty transposase variants with improved integration profiles (away from exons)

Activity-enhanced variant of hyeractive Sleeping Beauty transposase SB100X

Non-integrating alpharetrovirus-based vector particles for efficient RNA delivery and targeted gene modification

Maintenance of regulatory T cell phenotype by expression of IL-2 fusion protein

Reprogramming immune cells to develop allogenic CAR cell-based therapies

CRISPR-Cas induced immunosuppressant resistance in anti-viral T cell products for clinical application

High-level recombinant adeno-associated virus production

TCR/CD3-specific CAR NK-92 cells for purification of TCR-modified T cell products

The CXCR3alt-CXCL11 chemokine system for therapeutic use in solid cancer

BreakTag - Novel method for detection of ds-breaks and analysis of CRISPR-induced on- and off-target effects

CRISPR Switch: Inducible sgRNA expression for tightly regulated, efficient and safer CRISPR/Cas9 genome editing

CRISPR StAR: sgRNA expression vectors for reliable and reproducible in vivo screenings