Genome Architecture Mapping (GAM) (TO 03-00390)
03-00390
Genome Architecture Mapping (GAM). a, Discovering enhancer-promoter pairs in proximity. Bottom: example of a 2-element contact across 19Mb confirmed by DNAFISH. b-d, Schematic representation of the GAM concept.
Genome Architecture Mapping (GAM) is a novel genome-wide method for…
Novel diagnostic for Peripartum cardiomyopathy (PPCM) in pregnant women (TO 15-00411)
15-00411
Elevated PAI-1-serum and plasma levels in patients with PPCM compared to unaffected female and dilated cardiomyopathy (DCM) patients.
Extensive analysis revealed significantly elevated PAI-1 (plasminogen activator inhibitor-1) levels in PPCM…
AAV Vector Variants for Ocular Gene Delivery (TO 15-00648)
15-00648
Comparison of transduction with novel scAAV2 (M6) Cap5 capsid versus state-of-the art AAV(7m8) capsid reveals highly efficient expression of mCitrine in photoreceptor cells of the outer nuclear layer (ONL). (source: Büning et al.)
The technology describes novel variants…
