Novel therapy approach for treatment of lung fibrosis

Drug combinations to overcome therapy resistance in cancer

Expansion of pancreatic progenitors derived from human pluripotent stem cells und GMP-compliant conditions

Cystobactamids – novel antibacterials against gram-negative pathogens

Novel Labyrinthopeptins as anti-viral agents

Increased Availability and Efficacy of Aminoglycosides

Highly active Chlorotonil A Derivatives for the treatment of Malaria

Biodynamers enhance drug delivery

Oral Antimotilin-Based Inhibitors for Treating Helicobacter pylori Infections

First-in-Class S. aureus α-Hemolysin Inhibitors for Lung and Skin Infections 

Overcoming resistance - Innovative broad-spectrum inhibitors of Metallo- β-lactamases

Best-In-Class P. aeruginosa LasB virulence factor Inhibitors

Next-Generation Probiotics

Best-in-class Darobactin derivate against Gram-negative Bacteria

Novel Lectin-Targeting therapeutics and diagnostics for Pseudomonas aeruginosa infections

Novel vaccine vector platform for safe and effective immunization using a replication-deficient murine cytomegalovirus (MCMV)

Novel inhibitors of Cytomegalovirus

Inhibitors of Energy Coupling Factor (ECF) Transporters Against Gram-Positive Pathogens

Thiourea-Based Antibiotics against Acinetobacter baumannii

DeColi: Gut Decolonization of Multi-Resistant Escherichia coli

Novel ASO-Based mRNA Silencing Technology for Phage-Host Interaction Research

Stable Gene Transfer with Hyperactive Sleeping Beauty Transposase SB100X

Novel TPH inhibitors for the treatment of fibrotic diseases and pulmonary arterial hypertension (PAH)

Plasma cell-specific antibodies targeting BCMA for the treatment of multiple myeloma and autoimmune diseases

Improved Sleeping Beauty Transposon System for gene therapy: SB100X/pT4

Selective Inhibitors of Genotoxic Stress Induced IKK/NFκB Pathways for Cancer Therapy

Spacer-nick genome editing of hematopoietic stem and progenitor cells and T cells

Human TCR constructs for adoptive cell therapy of cancer

Jagaricin – a novel antifungal natural compound

Functionalized Nanoparticles for Viral Clearance

Nutritional compositions for treating dysfunction of liver fat metabolism – VAFD

Dream Complex Inhibitors for Treating Medical Conditions Induced by Circadian Rhythm Disruption

Liver stem cell generation for therapeutic applications

The physiological breast-milk proteins S100A8 and S100A9 promote an eubiotic gut state in infants

Novel treatment for sepsis in newborns

LS-COAT – an exceptionally efficient tumor vaccination approach

Engineered Immune Cells to Specifically Eliminate Undesired Immune Responses

AAV Vector Variants for Ocular Gene Delivery

Novel Treatment of Pulmonary Arterial Hypertension (PAH)

HLA-DR-specific γδ T-cell receptor to treat proliferative disorders of HLA-DR+ cells

Microelectrode array with combined optical stimulation

Ferulic acid derivatives as efficient neuroprotective agent and memory enhancer

Novel Therapy for Treatment of Alzheimer´s Disease

microRNA Signature Indicates Risk for Cognitive Decline

Treating dementia and other brain disorders with natural glycans

NMDAR targeted CAAR-T cell therapy

HERV inhibitors for use in tauopathies

T-cell therapy of MYD88L265P-dependent B-cell lymphoma

Next generation allogeneic CAR-NK cell platform for treatment of malignant diseases

Reprogramming immune cells for CAR cell-based therapies

Immunosuppressant resistance in anti-viral T cell products 

A novel immuno-oncology approach for induction and massive amplification of antigen-specific cytotoxic CD8⁺ T-cells

High-level recombinant adeno-associated virus production

The CXCR3alt-CXCL11 chemokine system for therapeutic use in solid cancer

Base editing enzymes for multiplex editing with simultaneous gene knock-in and knock-out

Method for direct measurement of functional avidity of T cells

Tyrolian algae extract with anti-inflammatory potential

NICHE-CAR-T: NR2F6 Immune Checkpoint Harnessing to Enhance CAR-T efficacy

Keratinophile photosensitizers for safe and rapid treatment of onychomycosis